PARTNERSHIP OPPORTUNITIES
Beryl currently has several unpartnered programs available for out-licenseing
HUMAN DISEASES
Innovation in treatment (osteoporosis) and a new indication (osteopenia)
Seeking expertise in other indications Medical Device Opportunities
HUMAN NUTRITION
Support healthy bone via nutritional supplement (DSHEA), food additive, medical food
Beryl Wellness
VETERINARY NUTRITION
Bone strength and wellness in companion and production animals
Beryl Animal Health
BERYL Development Path to the Bone Market
Beryl is the recipient of an investment from the Foundation for Prader-Willi Syndrome Research Venture Philanthropy Fund, which supports the advancement of therapeutic treatments to help children with PWS live more healthy and fulfilling lives.
BY THE NUMBERS
Osteoporosis Market
The market size for osteoporosis drugs was around $8 billion in 2020
An estimated 10 million Americans have been diagnosed with osteoporosis*
-
8.2 million are women over the age of 55
-
2.3 million people in the US and 21.3 million globally were known to suffer osteoporosis-related bone fractures in 2015 **,***
Fragility fractures create a $25 billion burden on the US healthcare system:
-
Second fractures incur $6.3 billion in Medicare costs
-
Hip fractures average $26,912, according to data from the American Academy of Orthopedic Surgeons
Only about 20% of osteoporotic patients are treated each year
Sources:
* National Osteoporosis Foundation https://www.nof.org/preventing-fractures/general-facts/what-women-need-to-know/
**“New Report on Burden of Osteoporosis Highlights Huge and Growing Economic and Human Toll of the Disease.” National Osteoporosis Foundation website. https://www.nof.org/news/new-report-on-burden-of-osteoporosis-highlights-huge-and-growing-economic-and-human-toll-of-the-disease/ (accessed March 23, 2020)
***Osteoporosis: A Global Health Crisis.” NBI Health website. https://nbihealth.com/osteoporosis-global-health-crisis/ (accessed March 23, 2020)
BY THE NUMBERS
Nutritional Supplements Market
31% of Adults 55 years+ report taking “bone health” supplements*
Total supplements market > $50B in 2015**
2013 – 2020 spend for US women over age 55:
Calcium & Vitamin D = $355.8M annually***
*CRN 2018 Consumer Survey on Dietary Supplements
**Source: Grand View Research, Inc.
***Source: Frost & Sullivan, Smart Prevention—Health Care Cost Savings Resulting from the Targeted Use of Dietary Supplements (Women Over 55), Figure 7.6 (2013)
BY THE NUMBERS
Osteopenia Market
Osteopenia (precursor to osteoporosis)
-
34 Million people (US) affected (Varacallo, et al, 2020)
-
50% of women who suffer bone fractures are osteopenic
-
Generally untreated or self-treated with calcium supplements, exercise
Sources: “Osteoporosis, Bone Fractures Cost Medicare $6.3 Billion.” Health Leaders Media website. https://www.healthleadersmedia.com/finance/osteoporosis-bone-fractures-cost-medicare-63b (accessed March 24, 2020).
